Occlusive Arterial Disease
Born

n this fourth volume in the prestigious "New Horizons" series, key aspects of hypertension, diabetes mellitus and the dyslipidemias as well as the nature of the interfaces among them are explored, with emphasis on the development of occlusive arterial disease. Scholarly state-of-the-art chapters by internationally acclaimed scientists and clinicians address the perplexing practical issues and unresolved problems from the clinical, cellular, molecular and genetic standpoints. The chapter topics within the domain of hypertension include future challenges in treatment, large artery mechanical function as a new target for treatment, the renin-angiotensin system as a paradigm for understanding genes that influence blood pressure, hypertension and cardiovascular risk in children and adolescents, vascular tone regulation in hypertension, and new developments regarding the relationship between endothelial function and hypertension.Diabetes mellitus and its complex relationship to occlusi ve arterial disease is critically explored in chapter topics which include recent research and clinical developments, advanced glycosylation end-products in the development of diabetic complications, insulin resistance, dyslipidemia and coronary heart disease in syndrome X, the genetics of diabetes and its complications, the research and clinical implications of oxidative (free radical) stress in diabetics, and controversial issues relating to the metabolic syndrome.The dyslipidemia chapters encompass a number of topics, which include a state-of-the-art examination of HDL and cardiovascular risk, a creative glimpse of molecular genetics into the 21st century, gene expression in coronary artery disease, mechanisms of atherosclerotic plaque destabilization, lipoprotein metabolism and remodeling, molecular mechanisms of action of drugs influencing lipoprotein metabolism, and the therapeutic implications of treshhold, linear or curvilinear models of cholesterol loweri ng.Additional chapters include a critical review of the causes of atherosclerosis, an examination of the role of thrombosis in occlusive arterial disease, and the controversial issue of infection as a pathogenic component of atherogenesis.This volume's outstanding assembly of essays should provide insights to cardiologists, clinicians, endocrinologists and research scientists interested in recent developments and future research directions in these important medical areas.

Informacje dodatkowe o Occlusive Arterial Disease:

Wydawnictwo: angielskie
Data wydania: b.d
Kategoria: Medycyna i zdrowie
ISBN: 978-3-7945-2048-0
Liczba stron: 0